Patterning the vertebrate axis

gastrulation and organizer activity

Hox gene complexes expressed along A-P axis

Hox gene expression establishes positional identity for germ layers

mesoderm forms notochord,

somites, lateral plate mesoderm

somites receive signals from notochord,neural tube, and ectoderm

somite develops into sclerotome

and dermomyotome

mesoderm induces neural plate

mesoderm imparts regional

identity to neural tube

regional patterns of Hox gene

expression subdivide the NT

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